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Projects and goals: - Identification and characterization of the adult "stem cell niche" in human and animal tendons
- Enhancement of the regenerative capacity of damaged tendons with adult stem cells
- Elucidating the role of nutrition (particularly sugars) in tendon healing, using an animal model (rat)
- Developing novel strategies for efficient healing of large bone defects, by transplantation of adult stem cells from various tissues and of biological factors ("small molecules") in a rat model.
- Reconstruction of functional tendon-bone connections
- Identification of molecular and cellular processes in the ageing tendon and bone
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